Join The Cellaviva Team

NextCell’s drug candidate ProTrans represents a platform technology for developing and manufacturing cell therapies to treat autoimmune diseases and inflammatory conditions. We have made the most progress with ProTrans for the treatment of type 1 diabetes, where both safety and efficacy in terms of preserving patients’ ability to produce their own insulin have been demonstrated in multiple clinical drug trials.

In addition to our own clinical trials, ProTrans is also being evaluated in other studies, including an academic study run by Uppsala University in collaboration with Linköping University and Lund University. The aim is to evaluate ProTrans for the treatment of young patients with type 1 diabetes.

The study has been approved and the first patient was included in Q4 2021. Uppsala University is sponsoring the study, which is paid for by research grants. NextCell is contributing ProTrans. The principal investigator is Professor Per-Ola Carlsson and co-investigators are Professor Helena Elding Larsson, Skåne University Hospital and Professor Johnny Ludvigsson, Linköping University Hospital

There are more and more parents who want to save stem cells, but unfortunately we are not able to send staff to the whole country (as we do in Denmark), so we are now setting up a network of experts in childbirth who, like us, want to help expectant parents have the birth they wish for. This would involve helping with the collection of the material that needs to be sent to the lab, in order to isolate the stem cells (haematopoietic and mesenchymal stem cells).

An example of how it works:

• The family comes into the maternity ward as usual, with a cellaviva box (containing all the medical instruments needed to make a collection of both cord blood and cord tissue).
• Before that, they have been in contact with our on-call service and we in turn with you.
• If you are able to make the collection, you will take over the contact with the family.
• 2 tubes of the mother’s venous blood must be collected, this is most easily made when the IV is inserted from the hospital side, and otherwise when it is convenient.
• The umbilical cord blood is collected immediately after the umbilical cord is clamped and cut (parents decide the time) and the umbilical cord tissue thereafter.
• Everything is packed as instructed, back into the cellaviva box.
• Collection report is written and put in the box.
• The box is sealed and you call our on-call number to say everything is ready, then leave the box with the parents.
• Our on-call staff will book medical transport to the lab.