Articles from Cellaviva

What is Chronic Active Epstein-Barr Virus (CAEBV)? CAEBV is a severe lymphoproliferative disorder caused by persistent EBV infection. It leads to systemic inflammation and organ damage. Role of Stem Cell Therapy: HSCT is the only curative treatment for severe or progressive CAEBV. Medical Insight: Transplant success depends on controlling viral load and systemic inflammation pre-HSCT [...]

What is Acute Undifferentiated Leukemia? A rare form of leukemia where the cells don't show clear markers to classify them as either lymphoid or myeloid. It is typically aggressive. Role of Stem Cell Therapy: HSCT is considered early in therapy, particularly when remission is achieved after induction chemotherapy. Medical Insight: Patients benefit from early donor [...]

What is Acute Biphenotypic Leukemia? Also known as Mixed Phenotype Acute Leukemia, this rare leukemia has cells showing both lymphoid and myeloid features, making diagnosis and treatment more complex. Role of Stem Cell Therapy: Due to its aggressive nature, HSCT is frequently recommended after remission is achieved. Medical Insight: Prognosis improves significantly with early transplant [...]

How an unborn baby’s cells can pass to the mother’s body during pregnancy, stay there for decades and help her resist neurodegenerative diseases such as Alzheimer’s.

The application of artificial intelligence in medical research is on the rise. In some of the recent research, advanced computer algorithms are being used to figure out why we age.

Tailor-made organs for human heart transplants using a patient’s own stem cells. This could mean an end to all organ shortages and anti-rejection drugs, as well as a revolution in cardiovascular surgery.

“Cancer and Alzheimer’s disease are like two sides of the same coin. The mechanisms are very similar, but the opposite of each other,” says Maria Ankarcrona, researcher at Karolinska Institutet’s Alzheimer’s Center in Huddinge.

“As a becoming mother, you want to be able to sign a contract with ‘the existence’ that nothing terrible can happen to your child. Unfortunately, reality does not look like that and we live in a time where life factors and the environment affect life “, answers Anja to the question why they believe that stem cell saving was an important step at the birth of their daughter.

The people exposed to nuclear fallout from the atomic bombs dropped on Hiroshima and Nagasaki during World War II suffered catastrophic health problems long after the actual explosions, which led researchers (who were looking for cures) to make an incredible discovery.

“Our vision is to improve treatment options for thousands, maybe millions of patients and reducing healthcare costs with the aid of stem cell therapy.” Mathias Svahn, CEO of Cellaviva and NextCell Pharma.

NextCell Pharma AB ("NextCell") today announces that the ProTrans-2 clinical trial met the primary endpoint. Patients treated with a single dose ProTrans show a statistically significant improved preservation of insulin production over 12 months, compared to patients treated with placebo (p-value < 0.05). A total of 15 patients were included in the ProTrans-2 trial. They […]

NextCell expects ProTrans to be an effective treatment for autoimmune diseases NextCell expects ProTrans to be an effective treatment for autoimmune diseases, other inflammatory conditions and in transplant reactions following organ transplantation. The drug candidate ProTrans is a stem cell product with umbilical cord cells. The cells are carefully selected with NextCell’s patent pending selection […]

Cellaviva and NextCell Pharma's Principal investigator receive the award as Child Diabetes Researcher of the Year by Swedish Crown Princess Victoria. Cellaviva’s Principal investigator for both our clinical studies with umbilical cord stem cells is called Per-Ola Carlsson. He is a Chief Physician and Professor of Medical Cell Biology and Medical Sciences at Uppsala University. […]

First studies testing the effect of mesenchymal stem cells in the treatment of COVID-19 have been published. In this contex, Dr. Leng and colleagues found that a single injection had an effect on 7 patients with COVID-19.

The Corona virus enters the host cell by binding to a receptor on the cells in the blood vessels. The body then responds as soon as the immune system recognizes that there are invaders and sends a number of different cell types and antibodies to try to destroy the virus. The result is a battlefield in every organ affected by the virus, between our immune system and the virus. In the case of COVID-19, the intensity of the battle can trigger a devastating immune reaction.

After the birth, the umbilical cord contains the same powerful stem cells that help your baby develop organs, blood, tissue, and an immune system during pregnancy.

It’s important to note that umbilical cord blood and cord tissue are rich in two distinct types of stem cells. Both types of stem cells play key roles in regenerative medicine, and each works in its own way.

The choice of stem cell source and donor always depends on available options and the disease to be treated. Therefore, it is Cellaviva’s recommendation to secure stem cells from both umbilical cord tissue and umbilical cord blood, if possible. The connective tissue-forming stem cells (Mesenchymal stem cells from the umbilical cord itself) When replacing damaged […]